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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
25.76
Human Site:
Y401
Identified Species:
40.48
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
Y401
E
E
K
E
D
E
D
Y
M
P
I
K
N
T
N
Chimpanzee
Pan troglodytes
XP_527529
607
69328
Y516
E
E
K
E
D
E
D
Y
M
P
I
K
N
T
N
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
Y401
E
E
K
E
D
E
D
Y
I
P
I
K
N
T
N
Dog
Lupus familis
XP_541147
492
57155
Y401
E
E
K
E
D
E
D
Y
M
P
I
R
N
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
Y401
E
E
K
E
D
E
E
Y
M
P
I
K
N
P
N
Rat
Rattus norvegicus
NP_001101927
357
40656
R267
F
S
R
F
G
P
I
R
S
C
E
V
I
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
Y397
D
E
E
E
D
D
K
Y
L
D
Q
H
S
V
S
Chicken
Gallus gallus
XP_419663
478
55881
K387
H
V
A
K
K
Q
K
K
K
K
H
Y
H
S
E
Frog
Xenopus laevis
Q6GLX7
477
54856
T379
E
E
V
R
K
K
N
T
N
K
G
V
S
R
E
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
Y363
K
S
K
Q
D
S
R
Y
E
L
L
L
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
N436
S
N
R
E
R
N
R
N
E
K
R
S
S
R
S
Honey Bee
Apis mellifera
XP_001121334
512
60307
Y394
K
N
N
S
E
C
S
Y
S
D
K
Y
I
E
K
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
K337
S
Q
Q
Q
E
A
P
K
R
R
Q
S
P
Q
R
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
R441
R
K
R
S
Q
G
M
R
H
E
E
D
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
G398
D
L
K
G
R
H
D
G
D
K
P
P
V
R
D
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
0
N.A.
26.6
0
13.3
20
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
66.6
26.6
33.3
53.3
N.A.
26.6
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% C
% Asp:
14
0
0
0
47
7
34
0
7
14
0
7
7
0
20
% D
% Glu:
40
47
7
47
14
34
7
0
14
7
14
0
0
14
14
% E
% Phe:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
7
0
7
0
0
7
0
0
7
0
% G
% His:
7
0
0
0
0
7
0
0
7
0
7
7
7
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
7
0
34
0
14
0
0
% I
% Lys:
14
7
47
7
14
7
14
14
7
27
7
27
0
0
7
% K
% Leu:
0
7
0
0
0
0
0
0
7
7
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
27
0
0
0
0
0
0
% M
% Asn:
0
14
7
0
0
7
7
7
7
0
0
0
34
0
34
% N
% Pro:
0
0
0
0
0
7
7
0
0
34
7
7
7
7
0
% P
% Gln:
0
7
7
14
7
7
0
0
0
0
14
0
0
7
0
% Q
% Arg:
7
0
20
7
14
0
14
14
7
7
7
7
0
27
7
% R
% Ser:
14
14
0
14
0
7
7
0
14
0
0
14
27
7
20
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
0
0
27
0
% T
% Val:
0
7
7
0
0
0
0
0
0
0
0
14
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _